Template:Tetanus Antibiotics
- Metronidazole 500mg IV (7.5mg/kg) q6hrs OR
- Clindamycin 600mg IV (7.5mg/kg) q6hrs
Penicillin
- Although once the drug of choice it is now no longer recommended since it may potentiate the effect of tetanus toxin by inhibiting the GABA receptors[1]
Pediatric
- Metronidazole 7.5mg/kg IV q6hrs (max 500mg/dose) x 7-10 days OR
- Clindamycin 10-13mg/kg IV q8hrs (max 900mg/dose)
- ↑ Ganesh Kumar AV. Benzathine penicillin, metronidazole and benzyl penicillin in the treatment of tetanus: a randomized, controlled trial .Ann Trop Med Parasitol. 2004 Jan;98(1):59-63 PMID 15000732