Template:PTA Antibiotics

Coverage for Streptococcus species, anerobes, Eikenella, H. influenza, S. auresus

Outpatient Options

• Clindamycin 300mg PO Q6hrs x7-10d
• Amoxicillin/Clavulanate 875 mg PO BID x 7-10d
• Penicillin V 500mg PO + Metronidazole 500mg QID

Inpatient Options

• Ampicillin/Sulbactam 3 gm (75mg/kg) IV four times daily
• Piperacillin/Tazobactam 4.5 gm IV TID
• Ticarcillin/Clavulanate 3.1 g IV QID
• Clindamycin 600-900mg IV TID
• Penicillin G 4 million units (50,000 units/kg) IV four times daily + Metronidazole 500mg IV three times daily

Pediatric Outpatient

• Clindamycin 30-40mg/kg/day PO divided TID (max 1.8g/day)
• Amoxicillin/Clavulanate 45mg/kg/day PO divided BID (max 875mg/dose)

Pediatric Inpatient

• Ampicillin/Sulbactam 50mg/kg IV q6hrs (max 3g/dose)
• Clindamycin 10-13mg/kg IV q8hrs (max 900mg/dose)
• Penicillin G 50,000 units/kg IV q6hrs (max 4 million units/dose) + Metronidazole 7.5mg/kg IV q8hrs (max 500mg/dose)