Template:Early Syphilis Treatment

• Penicillin G Benzathine 2.4 million units IM x 1
  • Repeat dose after 7 days for pregnant patients and HIV infection
• Doxycycline 100mg oral twice daily for 14 days as alternative

Congenital Syphilis:

• Penicillin G 50,000 units/kg IV q4-6h x 10-14 days
• Penicillin G Procaine 50,000 units/kg IM daily x 10-14 days
• Penicillin G Benzathine 50,000 units/kg IM x 1

Older Children:

• Penicillin G Benzathine 50,000 units/kg IM x 1 (max 2.4 million units)