Template:Anthrax antibiotics

Postexposure Prophylaxis

Patient should be vaccinated at day #0, #14, #28

• Ciprofloxacin 500mg PO q12hrs daily x 60 days OR
• Doxycycline 100mg PO q12hrs x 60 days

Cutaneous Anthrax (not systemically ill)

• Ciprofloxacin 500mg PO q12hrs x 60 days
• Doxycycline 100mg PO q12hrs x 60 days

Inhalation or Cutaneous with systemic illness

• Ciprofloxacin 400mg IV q12hrs x 60 days (1st line) OR
• Doxycycline 100mg IV q12hrs x 60days (only if allergic to ciprofloxacin) PLUS
  • Clindamycin 900mg IV q8hrs

Pediatric Postexpsoure Prophylaxis

• Ciprofloxacin 15mg/kg PO q12hrs x 60 days
• Doxycycline 2.2mg/kg PO q12hrs x 60 days

Pediatric Cutaneous Anthrax (not ill)

• Same as post exposure dosing and duration

Pediatric Inhalational or Cutaneous (systemically ill

• Ciprofloxacin 15mg/kg IV q12hrs (1st line) OR
• Doxycycline 2.2mg/kg IV q12hrs (only if allergic to cipro) PLUS
  • Clindamycin 7.5mg/kg q6hrs daily