Cyclopentolate

Administration

• Type: Cycloplegic, topical anticholinergics
• Dosage Forms:
• Routes of Administration: Ophthalmic
• Common Trade Names: Cyclogyl, Cylate, Pentolair

Adult Dosing

• 1-2 drops of 0.5%-2% solution, may repeat in 5-10min if needed

Pediatric Dosing

• Small infants: 1 drop of 0.5%-2% solution
• Children: 1-2 drops of 0.5%-2% solution, may repeat with 0.5%-1% solution in 5-10min if needed

Special Populations

• Pregnancy Rating: C
• Lactation risk: infant risk cannot be ruled out
• Renal dosing
• Hepatic dosing

Contraindications

• Allergy to class/drug
• Narrow-angle glaucoma or anatomically narrow angles

Adverse Reactions

Serious

• Tachyarrythmia, vasodilation
• Seizure
• Ataxia, confusion, psychosis
• Conjunctivitis
• Raised intraocular pressure

Common

• Blurred vision
• Burning sensation in eye
• Photophobia

Pharmacology

• Half-life:
• Metabolism:
• Excretion:

Mechanism of Action

• Anticholinergic, blocks the responses of the sphincter muscle of the iris and stimulation of ciliary body muscle, leading to cycloplegia and mydriasis.

Indications by Condition

The following table is automatically generated from disease/condition pages across WikEM.

Indication	Dose	Context	Route	Population
Corneal abrasion	1 drop 1% q6-8hr	Cycloplegic for large abrasions (>2mm) and/or severe pain	Topical ophthalmic	Adult