Olanzapine
Administration
- Type: Antipsychotic, second generation
- Dosage Forms:
- Routes of Administration:
- Common Trade Names: Zyprexa, Zydis
Adult Dosing
- Acute agitation (associated with schizophrenia or bipolar disorder): short-sting IM injection: initial dose 10 mg IM (consider lowering to 5 or 7.5 mg depending on clinical factors), additional dose 10 mg IM maybe considered. Allowed 2 hours after the first dose and 4 hours after the second dose to evaluate response (Maximum dose 30 mg/day)
- Special risk patients: consider lowering dose to 2.5 mg in patients who are debilitated, who have risk of hypotension or who maybe more pharmacodynamically sensitive to olanzapine.
- Schizophrenia
Pediatric Dosing
Special Populations
Renal Dosing
- Adult:
- Pediatric:
Hepatic Dosing
- Adult:
- Pediatric:
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
Common
Pharmacology
- Half-life:
- Metabolism:
- Excretion: