Anemia

Treatment

Hb <6 --> almost always transfuse

Hb >10 --> almost never transfuse

DDX

I. Hemorrhage

II. Destruction (hemolytic)

    A. Hereditary

    B. Acquired

III. Impaired Production

    A. Hypochromic (microcytic)

         -Fe deff, chronic disease, thalassemias, sideroblastic

    B. Aplastic/myelodysplastic (normocytic)

         -marrow failure, chemicals (ETOH), radiation, infection (HIV, parvo), RF

    C. Megaloblastic (macrocytic)

         -vit B12/folate def, drugs (chemo), HIV

Source

1/26/06 DONALDSON (adapted from Tintinalli's)