Ibutilide

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Adult Dosing

  • Loading dose = 1mg IV in 50mL D5W over 10min (wt>60kg)
  • Loading dose = 0.01mg/kg IV in 50mL D5W over 10min (wt<60kg)
  • Dose may be repeated 10min after completion of 1st dose

Contraindications

Indications

  • Rapid conversion of recent-onset A-fib/flutter to NSR

Mechanism of Action

  • Class III - Prolongs AP and refractory period

Adverse Drug Rxns

  • QT prolongation, V-tach, torsades
  • Observe for 4hr after infusion

Kinetics

  • Onset of action = 20-30min
  • Duration of action = 24hr

See Also

[[Antiarrythmics]

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