Hypertriglyceridemia

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Background

  • ~5% of acute pancreatitis caused by high TGs[1]
  • Etiologies
    • Familial hypertriglyceridemia, autosomal dominant with variable penetrance
    • Secondary forms
      • DM, obesity, EtOH, estrogen therapy
      • Hypothyroidism, ESRD, nephrotic syndrome, HIV, anti-HIV meds
  • TG levels > 2000 mg/dL almost always have both secondary and genetic form[2]

Management of Pancreatitis

  1. ↑ Yadav D, Pitchumoni CS. Issues in hyperlipidemic pancreatitis. J Clin Gastroenterology 2003;36:54-62.
  2. ↑ Yuan et al. Hypertriglyceridemia: its etiology, effects and treatment. CMAJ 2007;176:1113-1120.
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