Parkinson's disease

Revisión del 18:29 8 oct 2011 de Jswartz (discusión | contribs.) (Created page with "==Background== *Extrapyramidal movement disorder a/w reduced dopaminergic receptors in substantia nigra ==Clinical Features== *TRAP mnemonic: **Tremor (resting) ***Initially is ...")
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Background

  • Extrapyramidal movement disorder a/w reduced dopaminergic receptors in substantia nigra

Clinical Features

  • TRAP mnemonic:
    • Tremor (resting)
      • Initially is unilateral tremor of upper extremity, esp finger and thumb ("pill rolling")
      • Dissipates when intentional movement is performed
    • Rigidity (cogwheel)
      • Elicited by causing passive movement of limb through full range of motion
    • Akinesia
      • Slowness of voluntary movement
    • Posture/equilibrium impairment
      • Impaired ability to turn or change direction while walking

Treatment

  • Anticholinergics
    • Benztropine
  • Dopamine agonists
    • Levodopa

Source

Tintinalli

Obtenido de «https://www.wikem.org/w/index.php?title=Parkinson%27s_disease&oldid=6127»