Chloral hydrate

Revisión del 15:23 15 feb 2016 de 3amrbadawy (discusión | contribs.) (chloral pharm)

Background

  • Sedative-hypnotic used for insomnia
  • Binds GABA-A receptor
  • Active metabolite trichloroethanol (TCE)

Pharmacokinetics

  • Onset: 30-60 min
  • Duration: 4-8 hr
  • Half-Life: 5 mins (for chloral hydrate)
    • 8-11 hr (active metabolite)
  • Metabolism: Hepatic metabolism
  • Excretion: Mostly in urine; some feces
  • Potential toxic dose
    • <6 years old: 50 mg/kg
  • Adults: 3-10g

Clinical Features

Differential Diagnosis

Diagnosis

Management

Disposition

See Also

External Links

References

Obtenido de «https://www.wikem.org/w/index.php?title=Chloral_hydrate&oldid=52781»
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