Intralipid
General
- Type: Lipid emulsion
- Dosage Forms: 20% fat emulsion
- Routes of Administration: IV
- Common Trade Names: Intralipid
- Emergency department indications: Local anesthetic systemic toxicity, refractory hemodynamic instability 2/2 ingestion of cardiodepressive medications / toxins (i.e. Beta blocker or Calcium Channel Blocker)
Adult Dosing
- 1.5 ml/kg bolus[1]
- Followed by 0.25 ml/kg/min for 20 min or until hemodynamic stability is achieved.[2]
Pediatric Dosing
Special Populations
- Pregnancy Rating: C
- Lactation risk:
- Renal Dosing
- Adult
- Pediatric
- Hepatic Dosing
- Adult
- Pediatric
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
- Asystole (case reported) Error en la cita: Etiqueta de apertura
<ref>sin su correspondiente cierre</ref> - Hypertriglyceridemia[3]
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
- Mechanism of Action:
Comments
See Also
External Links
References
- ↑ Cave, G. Intravenous Lipid Emulsion as Antidote Beyond Local Anesthetic Toxicity: A Systematic Review. 2009. 16(9)815–824
- ↑ Dillane D, Finucane BT. Local anesthetic systemic toxicity. Can J Anaesth. 2010 Apr;57(4):368-80.
- ↑ Error en la cita: Etiqueta
<ref>no válida; no se ha definido el contenido de las referencias llamadasreview