Pain control



Agent Oral Parenteral
Step1. Mild Pain, Nonopiod, +/- Adjuvant
Acetaminophen 650mg q4-q6h prn or 1000mg q6h prn -
Aspirin 650mg q4-6h prn or 1000mg q6h prn -
Ibuprofen 400-800mg q6-8h prn -
Gabapentin (neuropathic Pain) Start 300mg qhs -
Step2. Mod Pain, Opiod for mild/mod pain, +/-nonopiod, +/-Adjuvant
Hydrocodone (5mg/Acetaminophen 325mg) 1-2 tabs PO q4-6h prn -
Oxycodone (5mg/Acetaminophen 325mg) 1-2 tabs PO q4h prn -
Oxycodone (Oxycontin) 5mg q4-6h -
Tramadol 50-100mg q4-6h (max 400mg/day) -
Step3. Severe Pain, Opiod for mod/sev pain, +/- nonopiod, +/-Adjuvant
Morphine 10-30mg q3-4h 0.1-0.2 mg/kg(up to 15mg q4h)
Morphine (controlled release) Start 30mg q8-12h , increase prn to 90-120mg q12h -
Fentanyl - 1 mcg/kg q1-3h
Hydromorphone (Dilaudid) 2-4mg q4-6h 1-4mg q4-6h
Levorphanol 2mg q6-8h

2mg q6-8h

^In elders, use a bulk laxative and give instructions regarding activity, hydration and close follow-up

See Also

Acute pain management

References

  • World Health Organization 3-Step Analgesia Ladder for Cancer & Washington Manual Intership Survival Guide, 2008