Cushing's syndrome

Revisión del 23:41 14 jun 2015 de Josgood (discusión | contribs.) (Created page with "==Background== *Hypercortisolism producing an array of non-specific symptoms *Exclude exogenous glucocorticoids and pregnancy ==Clinical Features== *Cutaneous: easy bruising,...")
(difs.) ← Revisión anterior | Revisión actual (difs.) | Revisión siguiente → (difs.)

Background

  • Hypercortisolism producing an array of non-specific symptoms
  • Exclude exogenous glucocorticoids and pregnancy

Clinical Features

  • Cutaneous: easy bruising, friable, striae, hyperpigmentation
  • Endocrine
    • Androgen excess causing hirsutism, oily skin, increased libido
    • Glucose intolerance
  • Metabolic: progressive obesity (esp. buffalo hump and supraclavicular fat pads obscuring clavicles)
  • Muscle: proximal muscle atrophy, weakness
  • Ophthalmologic: cataracts, increased intraocular pressure

Diagnosis

  • Outpatient: 24h urinary free cortisol or dexamethasone suppression test

References

UpToDate

Obtenido de «https://www.wikem.org/w/index.php?title=Cushing%27s_syndrome&oldid=40507»