Neutropenic enterocolitis

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Definition

Necrosis of bowel wall 2/2 microbial invasion


Pathophysiology

Usually involves the CECUM

Typically occurs 10-14d after cytotoxic therapy


Si/Sy

Fever

RLQ pain

Nausea

Vomiting

(mimics appy)


W/U

CT A/P: cecal distention and wall thickening


Treatment

Bowel rest

NG suction

IVF

Broad spec abx


Disposition

Surgical consultation (right hemicolectomy)


Prognosis

Mortality 50%