Clozapine

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Background

  • Atypical antipsychotic
  • Controls positive and negative symptoms of psychotic disorders

Complications

  • QT Prolongation
  • Agranulocytosis in 1%–2% of patients during initial treatment 3 months
    • Highest ~3 months into treatment and then decreases
  • Other potential side effects:
    • Dyslipidemia
    • Diabetes
    • Decreased seizure threshold

Also See

Sources

  • Lange Poisoning and Drug Overdose, 6th Ed., p. 443-4, 160-162
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