Immune reconstitution syndrome
Background
Immune reconstitution syndrome, or immune reconstitution inflammatory syndrome (IRIS), refers to the paradoxical worsening of pre-existing infections after antiretroviral therapy (ART) is intiated for HIV.[1] It occurs due to increases in T lymphocyte numbers that occurs after ART is started as well as increased immune response.
Clinical Features
Differential Diagnosis
Evaluation
Management
Disposition
See Also
External Links
References
- ↑ DeSimone JA, Pomerantz RJ, Babinchak TJ. Inflammatory reactions in HIV-1-infected persons after initiation of highly active antiretroviral therapy. Ann Intern Med. 2000;133(6):447–454. doi:10.7326/0003-4819-133-6-200009190-00013