Giant cell tumor

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Background

  • Benign tumor that is locally aggressive causing osteolytic destruction
  • Although classified as benign lesions, metastasis does occur in a small percentage of patients, typically to lungs
    • These are known as benign pulmonary implants as they do not carry the same poor prognostic implication as lung metastasis from other malignancies
  • 3 to 5 percent of all primary bone tumors
    • Around 20 percent in the Chinese population
  • Increased incidence in patients who have been diagnosed with Paget disease of the bone

Clinical Features

Differential Diagnosis

Evaluation

Management

Disposition

See Also

External Links

References