Osteosarcoma
Revisión del 21:32 21 nov 2019 de Mtjordan91 (discusión | contribs.) (Created page with "==Background== *Most common primary pediatric bone tumor; 3% of all childhood cancers *Around two-thirds of those diagnosed with non-metastatic disease under the age of 40 wil...")
Background
- Most common primary pediatric bone tumor; 3% of all childhood cancers
- Around two-thirds of those diagnosed with non-metastatic disease under the age of 40 will be long-term survivors or cured of the disease with appropriate treatment
- Survival is less than 20 percent with metastatic disease
- Bimodal as it peaks in early adolescence and over the age of 65
Pathophysiology
- Overproduction of osteoid and immature bone by malignant osteoblasts