Soil-transmitted helminthes

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Background

Clinical Features

Differential Diagnosis

Workup

Management

  • Ascaris: albendazole 400 mg x 1 dose OR mebendazole 100 mg BID x 3 days (both high efficacy)
  • Whipworm (Trichuris): albendazole 400 mg x 1 dose
    • Historically treated with albendazole or mebendazole, but monotherapy has low efficacy against Trichuris especially in heavy infections; higher cure rate achieved with oxantel pamoate-albendazole combination compared to any monotherapy in recent RCT [1]
  • Hookworm: albendazole 400 mg x 1 dose (high efficacy) OR mebendazole 500 mg x 1 dose (low to moderate efficacy)

Disposition

See Also

External Links

Sources

  1. Speich B, Ame S, et al. "Oxantel Pamoate–Albendazole for Trichuris Trichiura Infection." New England Journal of Medicine, 2014; 370: 610-620.