Xylazine toxicity

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Background

  • analogue of clonidine and agonist at alpha 2 adrenergic receptor
  • used for sedation, anesthesia, muscle relaxation and analgesia in animals
  • used as drug of abuse, usually drug adulterant

Clinical Features

  • bradycardia
  • respiratory depression
  • hypotension

Differential Diagnosis

  • other ingestions of sedative hypnotic agents

Evaluation

Management

  • maintain respiratory function and blood pressure, atropine for bradycardia

Disposition

  • admit for further monitoring

See Also

External Links

References

https://www.ncbi.nlm.nih.gov/pubmed/24769343