Rho(D) immune globulin

Background

Risk = >4-12wks

Treatment

1. 1st Trimester
   1. --> give 50 microgm
2. 2nd & 3rd Trimester
   1. --> give 300 microgm once and send Kleihauer-Betke test
   2. --> within 72hrs give additional 300 microgm/15 ml Rh-positive blood

Exceptions

1. prior sensitization of mother
2. known Rh-negative father
3. known Rh-negative fetus (from cord blood)