Platelet transfusion

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Features

  1. Transfusion should be type specific b/c platelets are bathed in plasma
    1. Non-type specific plts can be used but results in higher rate of complications
  2. Like pRBCs, plts can be leukocyte reduced or washed

Indications

  1. Plt count <10K in asymptomatic patients (unless due to ITP, TTP, or HIT)
  2. Plt count <15K with a coagulation disorder or minor bleeding
  3. Plt count <20K with major bleeding
  4. Plt count <50K with need for invasive procedure or surgery
  5. Plt count <100K with need for neurologic or cardiac surgery

Dose

  1. 1 unit raises count by 50K

See Also

Source

Tintinalli