EBQ:MATTERs Study

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incomplete Journal Club Article
Morrison J. et al. "Military Application of Tranexamic Acid in Trauma Emergency Resuscitation (MATTERs) Study". JAMA Surgery. 2012. 147(2):113-119.
PubMed Full text PDF

Clinical Question

Does administration of Tranexamic (TXA) acid in trauma patients with hemorrhage improve mortality in a wartime setting?

Conclusion

The use of TXA with blood component-based resuscitation following combat injury results in improved measures of coagulopathy and survival, a benefit that is most prominent in patients requiring massive transfusion

Major Points

Inclusion Criteria

Exclusion Criteria

Interventions

Outcome

Primary Outcomes

Secondary Outcomes

Subgroup analysis

Criticisms

Funding

Sources

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