Ethylene dibromide toxicity

Revisión del 22:12 1 may 2017 de Bisakson (discusión | contribs.) (Created page with "==Background== *Volatile liquid used in leaded gasoline and pesticides ==Mechanism of Toxicity== *Irritant, with potential to cause chemical burns *Respiratory tract irritati...")
(difs.) ← Revisión anterior | Revisión actual (difs.) | Revisión siguiente → (difs.)

Background

  • Volatile liquid used in leaded gasoline and pesticides

Mechanism of Toxicity

  • Irritant, with potential to cause chemical burns
  • Respiratory tract irritation if inhaled
  • Metabolites irreversibly bind to DNA and enzymes

Clinical Features

  • Pulmonary edema
  • Respiratory tract irritation
  • Eye irritation
  • Local swelling, inflammation with skin exposure
  • Diarrhea
  • Vomiting
  • Coma
  • Seizures
  • Rhabdomyolysis
  • Metabolic acidosis

Evaluation

  • Based on clinical history
  • Specific levels are not useful in the ED

Management

  • Decontamination measures
  • Administer activated charcoal
  • Treat wheezing, obstruction, pulmonary edema
  • No role for hemodialysis

References

  • Olson, K. Poisoning and Drug Overdose, 1999.
Obtenido de «https://www.wikem.org/w/index.php?title=Ethylene_dibromide_toxicity&oldid=133249»