Psilocybin toxicity

Psilocybin

A compound found in over 200 mushrooms that has mind altering properties similar to LSD. Commonly known as "magic mushrooms" or "shrooms". The mushroom are often taken recreationally for the euphoric and hallucinogenic effects. Typically grown in the Pacific Northwest and southern regions of the United States. For a typical dose (1mg) symptoms will last 1-3 hours.

Signs/Symptoms

Euphoria
Visual hallucinations
Lethargy
Depression
Synesthesia

Physical Effects

Pupil Dilation
Tachycardia
Hypertension
Hypotension
Nausea

Adverse Effects

Anxiety
Confusion
Disorientation
Agitation
Accidents

Toxicity

Low
280mg/kg
Therapeutic index of 641

Intoxication Treatment

Supportive Care
Pt's placed in a calm, quiet environment
Monitor Vitals
If worsening vitals or agitation treat with Benzodiazepines
Can be discharged if symptoms abate and vitals normalize

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