Beclomethasone

Administration

• Type: Corticosteroid
• Dosage Forms:
• Routes of Administration: inhalation, intranasal spray
• Common Trade Names: Qvar

Adult Dosing

• Asthma: 40 to 320 mcg by oral inhalation BID
• Rhinitis: 2 sprays (80 mcg/spray) in each nostril once daily

Pediatric Dosing

• Asthma, 6-11 yo: 40-80 mcg by oral inhalation BID
• Rhinitis, 4-11 yo: 1 spray (40 mcg/spray) in each nostril once daily

Special Populations

• Pregnancy Rating: C
• Lactation risk: Infant risk minimal
• Renal dosing: no adjustment
• Hepatic dosing: no adjustment

Contraindications

• Allergy to class/drug
• Not to be used as primary treatment for acute asthma exacerbation

Adverse Reactions

Serious

• Secondary hypocortisolism
• Cataract, glaucoma
• Bronchospasm

Common

• Headache

Pharmacology

• Half-life: 0.3-3h
• Metabolism: Hepatic via CYP3A4
• Excretion: Mostly fecal

Mechanism of Action

• Corticosteroid, reduces inflammation