Template:Diabetic foot infection antibiotics

Associated organisms include Staphylococcus, Streptococcus, Enterococcus, Enterobacteriaceae, Proteus, Bacteroides, and Pseudomonas, and Klebsiella

Superficial Mild Infections

• Clindamycin 450mg PO q8hrs daily x 14 days OR
• TMP/SMX 2DS tabs PO q12hrs daily x 14 days OR
• Doxycycline 100mg PO q12hrs daily x 14 days

Prior antibiotic treatment or moderate infections

• Amoxicillin/Clavulanate 875/125mg PO q12hrs + TMP/SMX 2DS tabs PO q12hrs daily x 14 days OR
• Clindamycin 450mg PO q8hrs + Ciprofloxacin 750mg PO q12hrs x 14 days

Inpatient Treatment

• Vancomycin 15-20mg/kg IV q12hrs plus
  • Ampicillin/Sulbactam 3g IV q6hrs OR
  • Piperacillin/Tazobactam 4.5g IV q8hrs OR
  • Ticarcillin/Clavulanate 3.1g IV q8hrs OR
  • Imipenem 500mg IV q6hrs OR
  • Metronidazole 500mg IV q8hrs PLUS
    • Cefepime 2g IV q12hrs OR
    • Ciprofloxacin 400mg IV q12hrs OR
    • Aztreonam 2g IV q8hrs