Diferencia entre revisiones de «Labetalol»

(Text replacement - "== " to "==")
(Text replacement - "HTN" to "hypertension")
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==Indications==
==Indications==
*HTN in setting of myocardial ischemia
*hypertension in setting of myocardial ischemia
*HTN in setting of neurologic injury
*hypertension in setting of neurologic injury
*HTN in setting of preeclampsia/eclampsia
*hypertension in setting of preeclampsia/eclampsia


==Contraindications==
==Contraindications==

Revisión del 18:24 30 jul 2016

General

Adult Dosing

  • Bolus dosing
    • 20mg IV followed by 40-80mg q10min up to total of 300mg
  • Infusion dosing
    • 0.5-2mg/min

Pediatric Dosing

Special Populations

  • Pregnancy Rating: C
  • Lactation: Compatible with breastfeeding
  • Renal Dosing
    • Adult
    • Pediatric
  • Hepatic Dosing
    • Adult
    • Pediatric

Indications

  • hypertension in setting of myocardial ischemia
  • hypertension in setting of neurologic injury
  • hypertension in setting of preeclampsia/eclampsia

Contraindications

  • Allergy to class/drug

Adverse Reactions

  • Orthostatic hypotension

Pharmacology

  • Half-life: 5-8hrs
  • Metabolism: Hepatic via conjugation
  • Excretion: Renal 55-60%
  • Mechanism of Action:
    • Class II - Nonselective beta blocker
    • Alpha1 blocker
  • Onset of action = 2-5min (IV)
  • Duration of action = 2-4hr (IV)

See Also

References