Diferencia entre revisiones de «Intravascular hemolytic tranfusion reaction»
(Text replacement - "==Diagnosis==" to "==Evaluation==") |
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| Línea 10: | Línea 10: | ||
{{Acute Allergic DDX}} | {{Acute Allergic DDX}} | ||
== | ==Evaluation== | ||
*Labs consistent with hemolysis | *Labs consistent with hemolysis | ||
Revisión del 18:50 23 jul 2016
Background
- Occurs due to ABO incompatibility
Clinical Features
- Back pain, headache, hypotension, dyspnea, pulmonary edema, bleeding, renal failure
Differential Diagnosis
Transfusion Reaction Types
- Acute
- Delayed
Acute allergic reaction
- Allergic reaction/urticaria
- Anaphylaxis
- Angioedema
- Anxiety attack
- Asthma exacerbation
- Carcinoid syndrome
- Cold urticaria
- Contrast induced allergic reaction
- Scombroid
- Shock
- Transfusion reaction
Evaluation
- Labs consistent with hemolysis
Management
- Stop transfusion
- Replace all tubing
- Risk of death is proportional to amount of incompatible blood received
- Maintain urine output with IVF (1-2 mL/kg/hr), mannitol, and furosemide as needed
- Treat shock with volume and vasopressors
- Treat coagulopathy with FFP