Diferencia entre revisiones de «Labetalol»
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Sin resumen de edición |
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==Pharmacology== | ==Pharmacology== | ||
*Half-life: | *Half-life: 5-8hrs | ||
*Metabolism: | *Metabolism: Hepatic via conjugation | ||
*Excretion: | *Excretion: Renal 55-60% | ||
*Mechanism of Action: | *Mechanism of Action: | ||
**Class II - Nonselective beta blocker | **Class II - Nonselective beta blocker | ||
Revisión del 21:13 2 may 2016
General
- Type: Beta blockers
- Dosage Forms:
- Common Trade Names:
Adult Dosing
- Bolus dosing
- 20mg IV followed by 40-80mg q10min up to total of 300mg
- Infusion dosing
- 0.5-2mg/min
Pediatric Dosing
Special Populations
- Pregnancy Rating: C
- Lactation: Compatible with breastfeeding
- Renal Dosing
- Adult
- Pediatric
- Hepatic Dosing
- Adult
- Pediatric
Indications
- HTN in setting of myocardial ischemia
- HTN in setting of neurologic injury
- HTN in setting of preeclampsia/eclampsia
Contraindications
- Allergy to class/drug
Adverse Reactions
- Orthostatic hypotension
Pharmacology
- Half-life: 5-8hrs
- Metabolism: Hepatic via conjugation
- Excretion: Renal 55-60%
- Mechanism of Action:
- Class II - Nonselective beta blocker
- Alpha1 blocker
- Onset of action = 2-5min (IV)
- Duration of action = 2-4hr (IV)