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**High incidence of allergy in HIV
**High incidence of allergy in HIV
*[[Dapsone]] 100mg PO once daily + [[TMP]] 5mg/kg PO q8hrs OR
*[[Dapsone]] 100mg PO once daily + [[TMP]] 5mg/kg PO q8hrs OR
**''caution: dapsone an cause methemoglobinemia''
**''caution: dapsone can cause methemoglobinemia''
*[[Atavaquone]] 750mg PO q12hrs  OR
*[[Atavaquone]] 750mg PO q12hrs  OR
*[[Primaquine]] 30mg PO q24hrs + [[Clindamycin]] 450mg PO q8hrs
*[[Primaquine]] 30mg PO q24hrs + [[Clindamycin]] 450mg PO q8hrs

Revisión actual - 18:28 22 feb 2016

Mild Disease

  • TMP/SMX 2 DS tablets PO q8hrs daily OR
    • High incidence of allergy in HIV
  • Dapsone 100mg PO once daily + TMP 5mg/kg PO q8hrs OR
    • caution: dapsone can cause methemoglobinemia
  • Atavaquone 750mg PO q12hrs OR
  • Primaquine 30mg PO q24hrs + Clindamycin 450mg PO q8hrs

Severe Disease

  • TMP/SMX 5mg/kg IV q8hrs daily x 21 days OR
  • Pentamidine 4mg/kg IV daily infused over 60 minutes OR
    • Watch for side effects of hypoglycemia and hypotension
  • Primaquine 30mg PO once daily + Clindamycin 900mg IV q8hrs daily

Prophylaxis

  • TMP/SMX 1 double strength tablet daily, but one single strength tablet daily or one double-strength three times weekly is acceptable.[1]
  1. CDC Guidelines for Prophylaxis Against Pneumocystis carinii Pneumonia for Children Infected with Human Immunodeficiency Virus http://www.cdc.gov/mmwr/preview/mmwrhtml/00001957.htm