Diferencia entre revisiones de «Herpes zoster ophthalmicus»

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==Background==
*Herpes zoster (HZV) ophthalmicus
*Occurs when the varicella-zoster virus is reactivated in the ophthalmic division of the trigeminal nerve
*10-25% of all zoster cases
*Most cases involve skin only, but serious ocular involvement can occur (if involves nasociliary branch)
**Hutchinson’s sign = pustules at tip of the nose
***Mild specificity for ocular involvement
***NOT sensitive for ocular involvement
==Diagnosis==
==Diagnosis==
corneal dedrite that stains or hazy edematous patch in cornea.
#Rash in distribution
#If corneal invovement
##Corneal dedrite on fluorescein stain
###Appear branching or ‘‘medusa-like’’ pattern with tapered ends
####In contrast to HSV dendrites, which have terminal bulbs


==Treatment==
==Treatment==
#Tx c topical trifluridine 8X/d for 7 d
#No corneal involvement
#debridement of dendrite may hasten recovery
##Topical antibiotics may prevent secondary infection
##Cool compresses/lubrication drops
##Ophtho followup (within 24hrs if any ocular involvement)
#Corneal involvement
##Artificial tears (preservative-free) Q1-2 hrs
##Ocular lubricant ointment QHS
##Consult ophtho regarding
###Systemic or topical antiviral agents
###Topical steroids (caution; only in consultation)
 
==Source==


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Revisión del 21:35 30 jul 2011

Background

  • Herpes zoster (HZV) ophthalmicus
  • Occurs when the varicella-zoster virus is reactivated in the ophthalmic division of the trigeminal nerve
  • 10-25% of all zoster cases
  • Most cases involve skin only, but serious ocular involvement can occur (if involves nasociliary branch)
    • Hutchinson’s sign = pustules at tip of the nose
      • Mild specificity for ocular involvement
      • NOT sensitive for ocular involvement

Diagnosis

  1. Rash in distribution
  2. If corneal invovement
    1. Corneal dedrite on fluorescein stain
      1. Appear branching or ‘‘medusa-like’’ pattern with tapered ends
        1. In contrast to HSV dendrites, which have terminal bulbs

Treatment

  1. No corneal involvement
    1. Topical antibiotics may prevent secondary infection
    2. Cool compresses/lubrication drops
    3. Ophtho followup (within 24hrs if any ocular involvement)
  2. Corneal involvement
    1. Artificial tears (preservative-free) Q1-2 hrs
    2. Ocular lubricant ointment QHS
    3. Consult ophtho regarding
      1. Systemic or topical antiviral agents
      2. Topical steroids (caution; only in consultation)

Source