Diferencia entre revisiones de «Clozapine»

Sin resumen de edición
Sin resumen de edición
Línea 5: Línea 5:


==Adult Dosing==
==Adult Dosing==
*Controls positive and negative symptoms of psychotic disorders
*Used for schizophrenia
*Off label use:
**Bipolar disorder
**Borderline personality disorder


==Pediatric Dosing==
==Pediatric Dosing==
Línea 23: Línea 18:
**Pediatric
**Pediatric


==Indications==
*Controls positive and negative symptoms of psychotic disorders
*Used for schizophrenia
*Off label use:
**Bipolar disorder
**Borderline personality disorder
==Contraindications==
==Contraindications==
*Allergy to class/drug
*Allergy to class/drug
Línea 50: Línea 51:
*[[Antipsychotic Medications]]
*[[Antipsychotic Medications]]


==Sources==
==References==
<references/>
<references/>
*Lange Poisoning and Drug Overdose, 6th Ed., p. 443-4, 160-162


[[Category:Drugs]]
[[Category:Drugs]]
[[Category:Psych]]
[[Category:Psych]]

Revisión del 03:38 29 ago 2015

General

  • Type: Atypical antipsychotic
  • Dosage Forms:
  • Common Trade Names:

Adult Dosing

Pediatric Dosing

Special Populations

  • Pregnancy Rating:
  • Lactation:
  • Renal Dosing
    • Adult
    • Pediatric
  • Hepatic Dosing
    • Adult
    • Pediatric

Indications

  • Controls positive and negative symptoms of psychotic disorders
  • Used for schizophrenia
  • Off label use:
    • Bipolar disorder
    • Borderline personality disorder

Contraindications

  • Allergy to class/drug

Adverse Reactions

  • QT prolongation
  • Myocarditis
  • Agranulocytosis in 1%–2% of patients during initial treatment 3 months
    • Highest ~3 months into treatment and then decreases
  • Other potential side effects:
    • Dyslipidemia
    • Diabetes
    • Decreased seizure threshold
  • "Other adverse cardiovascular and respiratory effects" [1]
  • "Increased mortality in elderly patients with dementia-related psychosis"[1]

Pharmacology

  • Half-life:
  • Metabolism:
  • Excretion:
  • Mechanism of Action:

See Also

References

  1. 1.0 1.1 "Clozaril (Clozapine) drug description - FDA approved labeling for prescription drugs and medications at RxList". Rxlist.com. Retrieved 2008-10-09.