Diferencia entre revisiones de «Steroid-induced psychosis»
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==Background== | ==Background== | ||
*In 718 hospitalized patients, 4.6% of patients on 40 mg or higher per day of prednisone had psychiatric symptoms<ref>Acute adverse reactions to prednisone in relation to dosage. Clin Pharmacol Ther. 1972;13:694-698.</ref> | *In 718 hospitalized patients, 4.6% of patients on 40 mg or higher per day of prednisone had psychiatric symptoms<ref>Acute adverse reactions to prednisone in relation to dosage. Clin Pharmacol Ther. 1972;13:694-698.</ref> | ||
*Incidence rises to 18.4% for patients receiving more than 80 mg per day | **Incidence rises to 18.4% for patients receiving more than 80 mg per day | ||
*Mechanism unproven but thought to be increased dopamine due to induction of tyrosin hydroxylase by corticosteroids<ref>J Pharm Technol. 2021 Apr; 37(2): 120–126. Published online 2020 Dec 2.</ref> | |||
==Clinical Features== | ==Clinical Features== | ||
Revisión del 12:59 13 mar 2024
Background
- In 718 hospitalized patients, 4.6% of patients on 40 mg or higher per day of prednisone had psychiatric symptoms[1]
- Incidence rises to 18.4% for patients receiving more than 80 mg per day
- Mechanism unproven but thought to be increased dopamine due to induction of tyrosin hydroxylase by corticosteroids[2]