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(Created page with "==Background== *Brown violin shape on cephalothorax (fiddleback) *In Southern midwestern US * ''Loxosceles'' family ===Mechanism=== *Venom contains variety of cytotoxic enzym...")
 
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==Clinical Features==
==Clinical Features==
#Bite is initially painless
*Bite is initially painless
#Mild reaction
*Mild reaction
##Most common
**Most common
##Mild erythematous lesion that later becomes firm and heals without scar
**Mild erythematous lesion that later becomes firm and heals without scar
#Severe reaction
*Severe reaction
##Begins w/ mild-severe pain several hrs after bite accompanied by erythema and swelling  
**Begins w/ mild-severe pain several hrs after bite accompanied by erythema and swelling  
##Hemorrhagic blister then forms surrounded by vasoconstriction-induced blanched skin
**Hemorrhagic blister then forms surrounded by vasoconstriction-induced blanched skin
##By day 3 or 4 hemorrhagic area may become ecchymotic
**By day 3 or 4 hemorrhagic area may become ecchymotic
###Leads to "red, white, and blue" sign (erythema, blanching, ecchymosis)
***Leads to "red, white, and blue" sign (erythema, blanching, ecchymosis)
##By end of first week ecchymotic area may become necrotic w/ eschar formation
**By end of first week ecchymotic area may become necrotic w/ eschar formation
#Systemic effects
*Systemic effects
##Rare
**Rare
##Occur predominantly in children 24-72hr after the bite
**Occur predominantly in children 24-72hr after the bite
###Include nausea/vomiting, fever, arthralgias, DIC, rhabdo, renal failure
***Include nausea/vomiting, fever, arthralgias, DIC, rhabdo, renal failure


==Differential Diagnosis==
==Differential Diagnosis==

Revisión del 23:25 11 mar 2015

Background

  • Brown violin shape on cephalothorax (fiddleback)
  • In Southern midwestern US
  • Loxosceles family

Mechanism

  • Venom contains variety of cytotoxic enzymes causing necrotic wound

Clinical Features

  • Bite is initially painless
  • Mild reaction
    • Most common
    • Mild erythematous lesion that later becomes firm and heals without scar
  • Severe reaction
    • Begins w/ mild-severe pain several hrs after bite accompanied by erythema and swelling
    • Hemorrhagic blister then forms surrounded by vasoconstriction-induced blanched skin
    • By day 3 or 4 hemorrhagic area may become ecchymotic
      • Leads to "red, white, and blue" sign (erythema, blanching, ecchymosis)
    • By end of first week ecchymotic area may become necrotic w/ eschar formation
  • Systemic effects
    • Rare
    • Occur predominantly in children 24-72hr after the bite
      • Include nausea/vomiting, fever, arthralgias, DIC, rhabdo, renal failure

Differential Diagnosis

Envenomations, bites and stings

Workup

Management

  1. Local wound care
  2. Abx are indicated only if signs of infection exist; secondary infections are uncommon
  3. Although some texts recommend Dapsone, it has been shown to be of limited benefit and is associated with hemolysis in G6PD patients and als methemoglobinemia

Disposition

See Also

External Links

Sources