Diferencia entre revisiones de «Brown recluse spider bite»
(Created page with "==Background== *Brown violin shape on cephalothorax (fiddleback) *In Southern midwestern US * ''Loxosceles'' family ===Mechanism=== *Venom contains variety of cytotoxic enzym...") |
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==Clinical Features== | ==Clinical Features== | ||
*Bite is initially painless | |||
*Mild reaction | |||
**Most common | |||
**Mild erythematous lesion that later becomes firm and heals without scar | |||
*Severe reaction | |||
**Begins w/ mild-severe pain several hrs after bite accompanied by erythema and swelling | |||
**Hemorrhagic blister then forms surrounded by vasoconstriction-induced blanched skin | |||
**By day 3 or 4 hemorrhagic area may become ecchymotic | |||
***Leads to "red, white, and blue" sign (erythema, blanching, ecchymosis) | |||
**By end of first week ecchymotic area may become necrotic w/ eschar formation | |||
*Systemic effects | |||
**Rare | |||
**Occur predominantly in children 24-72hr after the bite | |||
***Include nausea/vomiting, fever, arthralgias, DIC, rhabdo, renal failure | |||
==Differential Diagnosis== | ==Differential Diagnosis== | ||
Revisión del 23:25 11 mar 2015
Background
- Brown violin shape on cephalothorax (fiddleback)
- In Southern midwestern US
- Loxosceles family
Mechanism
- Venom contains variety of cytotoxic enzymes causing necrotic wound
Clinical Features
- Bite is initially painless
- Mild reaction
- Most common
- Mild erythematous lesion that later becomes firm and heals without scar
- Severe reaction
- Begins w/ mild-severe pain several hrs after bite accompanied by erythema and swelling
- Hemorrhagic blister then forms surrounded by vasoconstriction-induced blanched skin
- By day 3 or 4 hemorrhagic area may become ecchymotic
- Leads to "red, white, and blue" sign (erythema, blanching, ecchymosis)
- By end of first week ecchymotic area may become necrotic w/ eschar formation
- Systemic effects
- Rare
- Occur predominantly in children 24-72hr after the bite
- Include nausea/vomiting, fever, arthralgias, DIC, rhabdo, renal failure
Differential Diagnosis
Envenomations, bites and stings
- Hymenoptera stings (bees, wasps, ants)
- Mammalian bites
- Closed fist infection (Fight bite)
- Dog bite
- Marine toxins and envenomations
- Toxins (ciguatera, neurotoxic shellfish poisoning, paralytic shellfish poisoning, scombroid, tetrodotoxin
- Stingers (stingray injury)
- Venomous fish (catfish, zebrafish, scorpion fish, stonefish, cone shells, lionfish, sea urchins)
- Nematocysts (coral reef, fire coral, box jellyfish, sea wasp, portuguese man-of-war, sea anemones)
- Phylum porifera (sponges)
- Bites (alligator/crocodile, octopus, shark)
- Scorpion envenomation
- Reptile envenomation
- Spider bites
Workup
Management
- Local wound care
- Abx are indicated only if signs of infection exist; secondary infections are uncommon
- Although some texts recommend Dapsone, it has been shown to be of limited benefit and is associated with hemolysis in G6PD patients and als methemoglobinemia
