Diferencia entre revisiones de «Chondrosarcoma»
| Línea 7: | Línea 7: | ||
*Overproduction of chondroid matrix in the medullary cavity | *Overproduction of chondroid matrix in the medullary cavity | ||
==Clinical Features== | ==Clinical Features== | ||
*Lesions commonly in the pelvis and central skeleton | |||
*Occurs in patients over 40 years-old with a male predominance | |||
*Often will present with local swelling and pain or a pathologic fracture | |||
*Very slow growing tumors | |||
==Differential Diagnosis== | ==Differential Diagnosis== | ||
Revisión del 22:26 21 nov 2019
Background
- Third most common primary bone malignancy after multiple myeloma and osteosarcoma
- Around ninety percent of chondrosarcomas are of low metastatic potential
- Osteochondromas and enchondromas can be precursors lesions
Pathophysiology
- Overproduction of chondroid matrix in the medullary cavity
Clinical Features
- Lesions commonly in the pelvis and central skeleton
- Occurs in patients over 40 years-old with a male predominance
- Often will present with local swelling and pain or a pathologic fracture
- Very slow growing tumors