Diferencia entre revisiones de «Trientine»
(Creation of page) |
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| Línea 19: | Línea 19: | ||
==Special Populations== | ==Special Populations== | ||
===[[Drug pregnancy categories|Pregnancy Rating]]=== | ===[[Drug pregnancy categories|Pregnancy Rating]]=== | ||
* | *Category C; clinical caution advised during pregnancy | ||
===Lactation risk=== | ===Lactation risk=== | ||
Revisión actual - 23:09 23 sep 2019
Administration
- Type: Antidote
- Dosage Forms: Capsule 250mg
- Routes of Administration: Oral
- Common Trade Names: Syprine
Adult Dosing
Wilson's disease
- 750-1250 mg/day PO divided BID-QID
- Max: 2000 mg/day
Pediatric Dosing
Wilson's disease
- < 13 yo
- 20 mg/kg/day PO divided BID-TID
- 13 yo +
- 750-1250 mg/day divided BID-QID
Special Populations
Pregnancy Rating
- Category C; clinical caution advised during pregnancy
Lactation risk
- Caution advised while breastfeeding
Renal Dosing
- Adult: Not defined
- Pediatric: Not defined
Hepatic Dosing
- Adult: Not defined
- Pediatric: Not defined
Contraindications
- Allergy to class/drug
- Rheumatoid arthritis
- Biliary cirrhosis
- Cystinuria
Adverse Reactions
Serious
- May occur, but none have been reported
Common
- Iron-deficient anemia
Lupus erythematosus
- Contact dermatitis
Pharmacology
- Half-life: Unknown
- Metabolism: Unknown
- Excretion: Urine
Mechanism of Action
- Chelates copper for excretion from the body