Diferencia entre revisiones de «Metoprolol»
| Línea 21: | Línea 21: | ||
*Renal Dosing | *Renal Dosing | ||
**Adult | **Adult | ||
*** No adjustment necessary | |||
**Pediatric | **Pediatric | ||
*** No adjustment necessary | |||
*Hepatic Dosing | *Hepatic Dosing | ||
**Adult | **Adult | ||
*** Not defined however consider reduced dose due to hepatic metabolism | |||
**Pediatric | **Pediatric | ||
*** Not defined however consider reduced dose due to hepatic metabolism | |||
==Contraindications== | ==Contraindications== | ||
Revisión del 17:26 2 abr 2019
General
- Type: Beta blockers
- Dosage Forms: Tablet: 25 mg, 37.5 mg, 50 mg, 75mg, 100 mg. IV: variable
- Common Trade Names: Lopressor
Adult Dosing
Hypertension
- 50-200 mg PO bid
CHF
- 12.5-100 mg PO bid
Migraine prophylaxis
- 25-100 mg PO bid
Pediatric Dosing
Special Populations
- Pregnancy Rating:
- Lactation:
- Renal Dosing
- Adult
- No adjustment necessary
- Pediatric
- No adjustment necessary
- Adult
- Hepatic Dosing
- Adult
- Not defined however consider reduced dose due to hepatic metabolism
- Pediatric
- Not defined however consider reduced dose due to hepatic metabolism
- Adult
Contraindications
- Allergy to class/drug
- Sinus bradycardia
- AV blocks
- decompensated acute CHF
- cardiogenic shock
- hypotension
Adverse Reactions
Serious
- CHF
- bradycardia
- AV block
- bronchospasm
Common
- fatigue
- dizziness
- depression
- dyspnea
Pharmacology
- Half-life: 3-7 hours
- Metabolism: Liver
- Excretion: Renal
- Mechanism of Action: Selective Beta-1 adrenergic receptor antagonist