Diferencia entre revisiones de «Nitroprusside»
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==Adult Dosing== | ==Adult Dosing== | ||
*Start 0.5 mcg/kg/min IV, increasing 0.5 mcg/kg/min q5 min | |||
*Usual dosage 3-4 mcg/kg/min IV | |||
*Max dose 10 mcg/kg/min for 10 min | |||
==Pediatric Dosing== | ==Pediatric Dosing== | ||
Revisión del 23:18 6 oct 2018
Background
- Sodium nitroprusside is primarily used as a potent vasodilator.
- Works predominantly in arterioles and venules as a result of its breakdown to nitric oxide (NO).[1]
- Nitric oxide reduces both total peripheral resistance and venous return, thus decreasing both preload and afterload
- Thiocyanate level when checking for toxicity
Adult Dosing
- Start 0.5 mcg/kg/min IV, increasing 0.5 mcg/kg/min q5 min
- Usual dosage 3-4 mcg/kg/min IV
- Max dose 10 mcg/kg/min for 10 min
Pediatric Dosing
Contraindications
Indications
Mechanism of Action
Potent arteriolar dilation from its active metabolite, nitric oxide (NO).
Adverse Drug Reactions
Kinetics
See Also
- ↑ "nitroprusside sodium (Rx) - Nipride, Nitropress, more..". Medscape Reference. WebMD. Retrieved 20 November 2013.