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| ==Background==
| | #REDIRECT[[Dialysis disequilibrium syndrome]] |
| *Characterized by neurological symptoms that is thought to be secondary to cerebral edema affecting dialysis patients
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| *Tends to occur in patients who are initially started on dialysis, particularly with high initial BUN
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| *Symptoms are thought to be secondary to the development of cerebral edema possibly due to urea removal during dialysis and from a decreased in pH in the cerebral intracelluar environment
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| ==Clinical Features==
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| *Signs and symptoms develop during or after dialysis or during renal replacement therapy, usually self limited but can occasionally progress
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| *Headache
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| *Nausea
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| *Visual disturbances
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| *Asterixis
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| *Altered mental staus
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| *Seizures
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| *Coma
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| *Muscle Cramps
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| ==Differential Diagonsis==
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| *[[Hypoglycemia]]
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| *[[Hyponatremia]]
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| *[[Hypocalcemia]]
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| *[[Uremia]]
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| *Intracranial Bleed
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| *[[Hypertensive Emergency]]
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| *[[Stroke]]
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| *Supratheurapeutic Medication Effects
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| *PRES
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| ==Evaluation==
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| *Clinical Diagonosis
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| *Bedside Glucose
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| *CBC
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| *Chem-10
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| *Liver Panel
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| *CT Brain
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| ==Management==
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| *Supportive in most cases
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| *Limit the rate of urea removal during first few session of dialysis to prevent dysequilibrium syndrome
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| *For severe symptoms such as seizure, consider stopping dialysis
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| ==Disposition==
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| *Most cases can be discharged with followup
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| ==References==
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| <references/>
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| *Mailloux L, et al. Dialysis Dysequilibrium Syndrome. UpToDate. Waltham, Mass.: UpToDate; 2017. www.uptodate.com. Accessed April 13, 2017.
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| [[Category:Renal]]
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| [[Category:Neurology]]
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