Diferencia entre revisiones de «Intravascular hemolytic tranfusion reaction»
(Text replacement - "==Diagnosis==" to "==Evaluation==") |
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==Background== | ==Background== | ||
*Occurs due to ABO incompatibility | *Occurs due to ABO incompatibility | ||
*High mortality. 1:30 may die. | |||
==Clinical Features== | ==Clinical Features== | ||
Revisión del 21:38 26 nov 2016
Background
- Occurs due to ABO incompatibility
- High mortality. 1:30 may die.
Clinical Features
- Back pain, headache, hypotension, dyspnea, pulmonary edema, bleeding, renal failure
Differential Diagnosis
Transfusion Reaction Types
- Acute
- Delayed
Acute allergic reaction
- Allergic reaction/urticaria
- Anaphylaxis
- Angioedema
- Anxiety attack
- Asthma exacerbation
- Carcinoid syndrome
- Cold urticaria
- Contrast induced allergic reaction
- Scombroid
- Shock
- Transfusion reaction
Evaluation
- Labs consistent with hemolysis
Management
- Stop transfusion
- Replace all tubing
- Risk of death is proportional to amount of incompatible blood received
- Maintain urine output with IVF (1-2 mL/kg/hr), mannitol, and furosemide as needed
- Treat shock with volume and vasopressors
- Treat coagulopathy with FFP