Diferencia entre revisiones de «Cushing's syndrome»
(Text replacement - "==Diagnosis==" to "==Evaluation==") |
Sin resumen de edición |
||
| Línea 18: | Línea 18: | ||
<references/> | <references/> | ||
[[Category: | [[Category:Endocrinology]] | ||
Revisión del 05:22 17 ago 2017
Background
- Hypercortisolism producing an array of non-specific symptoms
- Exclude exogenous glucocorticoids and pregnancy
Clinical Features
- Cutaneous: easy bruising, friable, striae, hyperpigmentation
- Endocrine
- Androgen excess causing hirsutism, oily skin, increased libido
- Glucose intolerance
- Metabolic: progressive obesity (esp. buffalo hump and supraclavicular fat pads obscuring clavicles)
- Muscle: proximal muscle atrophy, weakness
- Ophthalmologic: cataracts, increased intraocular pressure
Evaluation
- Outpatient: 24h urinary free cortisol or dexamethasone suppression test
References
UpToDate