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A peptide that mimics endogenous somatostatin. Somatostatin is released by the pancreas, pyloric antrum, and duodenum and inhibits growth hormone, gastrin, Vasoactive intestinal peptide (VIP), gastrin, serotonin, and decreases Insulin like growth factor-1 (IGF-1) and decreases splanchnic blood flow.
A peptide that mimics endogenous somatostatin. Somatostatin is released by the pancreas, pyloric antrum, and duodenum and inhibits growth hormone, gastrin, Vasoactive intestinal peptide (VIP), gastrin, serotonin, and decreases Insulin like growth factor-1 (IGF-1) and decreases splanchnic blood flow.
==Comments==
==Comments==
Although used in the ED mainly for sulfonylurea overdose and vatical bleeding, it is used in outpatient and inpatient medicine for the treatment of acromegaly, carcinoid tumors, and VIPomas


==See Also==
==See Also==

Revisión del 21:03 11 may 2016

Administration

  • Type: Octapeptide
  • Dosage Forms:
  • Routes of Administration: IV, IM
  • Common Trade Names: Sandostatin, Sandostatin LAR

Adult Dosing

Pediatric Dosing

Special Populations

Renal Dosing

  • Adult:
  • Pediatric:

Hepatic Dosing

  • Adult:
  • Pediatric:

Contraindications

  • Allergy to class/drug

Adverse Reactions

Serious

Common

Pharmacology

  • Half-life:
  • Metabolism:
  • Excretion:

Mechanism of Action

A peptide that mimics endogenous somatostatin. Somatostatin is released by the pancreas, pyloric antrum, and duodenum and inhibits growth hormone, gastrin, Vasoactive intestinal peptide (VIP), gastrin, serotonin, and decreases Insulin like growth factor-1 (IGF-1) and decreases splanchnic blood flow.

Comments

Although used in the ED mainly for sulfonylurea overdose and vatical bleeding, it is used in outpatient and inpatient medicine for the treatment of acromegaly, carcinoid tumors, and VIPomas

See Also

References