Diferencia entre revisiones de «Weakness»

Línea 50: Línea 50:
==DDX==
==DDX==
# UPPER
# UPPER
## Multiple sclerosis
## [[Multiple Sclerosis]]
## Poliomyelitis
## Poliomyelitis
## [[ALS]] (upper & lower motor)
## [[ALS]] (upper & lower motor)
Línea 57: Línea 57:
### Cord compression
### Cord compression
## Painless
## Painless
### Transverse myelitis
### [[Transverse Myelitis]]
### Spinal cord infarct
### Spinal cord infarct
### Intramedullary tumor
### Intramedullary tumor
# NERVE
# NERVE
## Guillian-Barre
## [[Guillian-Barre]]
## Toxic neuropthy (Ciguatera)
## Toxic neuropthy (Ciguatera)
## Tick paralysis
## Tick paralysis
Línea 67: Línea 67:
## Porphyria
## Porphyria
# MOTOR END PLATE
# MOTOR END PLATE
## Myasthenia gravis
## [[Myasthenia Gravis]]
## Botulism (descending)
## [[Botulism]] (descending)
## Organophosphate poisoning
## [[Organophosphate Poisoning]]
## Lambert-Eaton
## [[Lambert-Eaton]]
# MUSCLE
# MUSCLE
## Painful
## Painful
### Rhabdo
### [[Rhabdo]]
### Alcoholic
### [[Alcoholic]]
### Myopathy
### Myopathy
### Polymyositis
### Polymyositis
Línea 80: Línea 80:
### Toxins
### Toxins
### Hypophos
### Hypophos
### Hypo-kalemia
### [[Hypokalemia]]
### Polymyalgia rheum
### Polymyalgia rheum
## Painless
## Painless
Línea 87: Línea 87:
# MIXED
# MIXED
## Upper & Lower Motor Neuron
## Upper & Lower Motor Neuron
### ALS
### [[ALS]]
## Sensory & Motor
## Sensory & Motor
###
###
# NON-NEUROMUSCULAR
# NON-NEUROMUSCULAR
## MI
## [[MI]]
## Resp failure
## Resp failure
## Sepsis
## [[Sepsis]]
## Dehydration
## Dehydration
## Anxiety
## Anxiety

Revisión del 08:34 5 dic 2011

Background

Acute/Generalized

Workup

  1. cbc
  2. chem 10 (esp. K, Mg, Ca, Phos)
  3. ecg
  4. +/- CK (r/o myopathy)
  5. +/- FVC (eval impending resp failure, i.e. Myasthenia)
  6. +/- ABG/CT/LP/TSH/UA (rhabdo)

Diagnosis

Upper Motor Neuron

  • BRAIN
    • Weakness - variable
    • Bowel/Bladder -
    • Reflexes - increased
    • Sens - diminished
    • Pain - no
    • Asymmetric/unilateral
  • CORD
    • Weakness - fixed level
    • Bowel/Bladder - YES
    • Reflexes - increased
    • Sens - diminished
    • Pain - +/-

Lower Motor Neuron

  • NERVE
    • Weakness - distal and ascends
    • Bowel/Bladder - NO
    • Reflexes - diminished
    • Sens - nl/paresthesias
    • Pain - no

End-Plate/Muscle

  • MOTOR END PLATE
    • Weakness - head and descends
    • Bowel/Bladder - NO
    • Reflexes - nl/diminished
    • Sens - nl
    • Pain - no
  • MUSCLE
    • Weakness - proximal
    • Bowel/Bladder - NO
    • Reflexes - nl/diminished
    • Sens - nl
    • Pain - +/-

DDX

  1. UPPER
    1. Multiple Sclerosis
    2. Poliomyelitis
    3. ALS (upper & lower motor)
  2. CORD
    1. Painful
      1. Cord compression
    2. Painless
      1. Transverse Myelitis
      2. Spinal cord infarct
      3. Intramedullary tumor
  3. NERVE
    1. Guillian-Barre
    2. Toxic neuropthy (Ciguatera)
    3. Tick paralysis
    4. Diabetic neuropathy
    5. Porphyria
  4. MOTOR END PLATE
    1. Myasthenia Gravis
    2. Botulism (descending)
    3. Organophosphate Poisoning
    4. Lambert-Eaton
  5. MUSCLE
    1. Painful
      1. Rhabdo
      2. Alcoholic
      3. Myopathy
      4. Polymyositis
      5. Dermatomyositis
      6. Toxins
      7. Hypophos
      8. Hypokalemia
      9. Polymyalgia rheum
    2. Painless
      1. Familial periodic paralysis
      2. Endocrine
  6. MIXED
    1. Upper & Lower Motor Neuron
      1. ALS
    2. Sensory & Motor
  7. NON-NEUROMUSCULAR
    1. MI
    2. Resp failure
    3. Sepsis
    4. Dehydration
    5. Anxiety
    6. Fibromyalgia/chronic fatigue
    7. Malignancy

Emergent Threat/ED Workup

  1. CORD
    1. paralysis
    2. MRI, neurologist
  2. NERVE
    1. resp failure
    2. FEV1, airway mgt, ticks?, neurologist
  3. MOTOR END PLATE
    1. resp failure
    2. FEV1, airway mgt, Tensilon Test?
  4. MUSCLE
    1. Rhabdo
    2. urine myoglobin, serum CK, BUN/Cr
    3. serum K+

Intubation Indications

  1. Severe fatigue
  2. Inability protect airway
  3. Rapidly increasing PaCO2
  4. Hypoxemia despite O2
  5. FVC <12 mL/kg
  6. Neg Insp Force <20 cm H2O

Source

2/26/06 DONALDSON (adapted from Rosen, Lampe, Birnbaumer)

adapted from Hockberger