Diferencia entre revisiones de «Unfractionated heparin»
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##[[NSTEMI]] | ##[[NSTEMI]] | ||
##[[STEMI]] | ##[[STEMI]] | ||
==See Also== | |||
*[[Low Molecular Weight Heparin]] | |||
==Source == | ==Source == | ||
Revisión del 06:59 21 oct 2011
Background
- Binds to and activates antithrombin which in turns inactivates factor Xa and thrombin
- Half-life is 30-150min
- Must give IV (not subq) for acute thromboembolic disease
- Safe in pregnancy
- Unpredictable anticoagulation effect
- Must monitor w/ PTT; therapeutic range is 1.5-2.5x normal value
Treatment
See Also
Source
Tintinalli