Diferencia entre revisiones de «Disulfiram effect»

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==Background==
==Background==
The disulfiram effect refers to medication adverse effect that are similar to those seen with disulfiram (trade names Antabuse, Antabus).  Disulfiram is a drug that is used to support the treatment of chronic alcoholism by producing an acute sensitivity to [[Ethanol|ethanol]]. Disulfiram works by inhibiting the enzyme acetaldehyde dehydrogenase, which means many of the effects of a "hangover" are felt immediately after alcohol is consumed. The disulfiram effect refers to similar symptoms seen when other medications are mixed with ethanol.
*Disulfiram (Trade names: '''Antabuse''', '''Antabus''') - causes an acute reaction in the presence of [[ethanol]].
**Works by inhibiting acetaldehyde dehydrogenase → buildup of acetaldehyde → unpleasant effects.
**Designed to assist in alcohol cessation.
 
==Clinical Features==
 
 
==Differential Diagnosis==
 
 
==Diagnosis==
*Clinical diagnosis


==Medications with Similar Effects==
==Medications with Similar Effects==
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* Antifungals ([[Griseofulvin]])
* Antifungals ([[Griseofulvin]])


==Treatment==
==Management==
Care is primarily supportive.
*Supportive care
 
==Disposition==
 
 
==See Also==
[[Ethanol toxicity]]
 
==References==
<References/>


[[Category:Drugs]]
[[Category:Drugs]]
[[Category:Tox]]

Revisión del 05:16 9 ago 2015

Background

  • Disulfiram (Trade names: Antabuse, Antabus) - causes an acute reaction in the presence of ethanol.
    • Works by inhibiting acetaldehyde dehydrogenase → buildup of acetaldehyde → unpleasant effects.
    • Designed to assist in alcohol cessation.

Clinical Features

Differential Diagnosis

Diagnosis

  • Clinical diagnosis

Medications with Similar Effects

Management

  • Supportive care

Disposition

See Also

Ethanol toxicity

References