Ivermectin

General

• Type: antiparasitic
• Dosage Forms: 3
• Common Trade Names: Stromectol

Adult Dosing

strongyloidiasis: 0.2 mg/kg PO x1

onchocerciasis: 0.15 mg/kg PO x1

scabies, non-crusted: 0.2 mg/kg PO x1

scabies, crusted: 0.2 mg/kg PO x1 on days 1,2,8,9,15

pediculosis capitis: 0.2 mg/kg pO q10 days x2 doses

pediculosis corporis: 12 mg PO q7 days x3 doses

pediculosis pubis: 0.25 mg/kg PO q2wk x2 doses

Special Populations

• Pregnancy Rating:
• Lactation:
• Renal Dosing
  • Adult
  • Pediatric
• Hepatic Dosing
  • Adult
  • Pediatric

Contraindications

• Allergy to class/drug

Adverse Reactions

Serious

• hypotension, orthostatic
• tachycardia
• seizures
• Stevens-Johnson syndrome
• toxic epidermal necrolysis
• asthma exacerbation
• vision loss
• conjunctival hemorrhage
• hepatitis

Common

• pruritus
• rash
• fever
• edema
• lymphadenopathy
• headache
• myalgia
• dizziness
• tachycardia
• abnormal eye sensation
• limbitis
• conjunctivitis
• ocular inflammation
• hypotension, orthostatic
• ALT, AST elevated
• eosinophilia

Pharmacology

• Half-life:
• Metabolism:
• Excretion:
• Mechanism of Action: