Diferencia entre revisiones de «Mupirocin»
(Replace manual dosing with dynamic SMW tables (Adult + Pediatric)) Etiqueta: Revertido |
(Restore original dosing content alongside dynamic SMW tables) Etiqueta: Revertido |
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| Línea 6: | Línea 6: | ||
==Adult Dosing== | ==Adult Dosing== | ||
===[[Impetigo]]=== | |||
*apply ointment TID x 7-14 days | |||
===[[Skin infections]], bacterial=== | |||
*apply cream TID x 10 days | |||
===Indications by Disease=== | ===Indications by Disease=== | ||
{{#ask: [[Has DrugName::Mupirocin]] [[Has Population::Adult]] | {{#ask: [[Has DrugName::Mupirocin]] [[Has Population::Adult]] | ||
|?Treats disease=Disease | |?Treats disease=Disease | ||
|?Has Dose=Dose | |?Has Dose=Dose | ||
|?Has Context=Context | |?Has Context=Context | ||
|format=table | |format=table | ||
|limit=50 | |limit=50 | ||
|mainlabel=- | |mainlabel=- | ||
|headers=show | |headers=show | ||
|sort=Treats disease | |sort=Treats disease | ||
}} | }} | ||
==Pediatric Dosing== | ==Pediatric Dosing== | ||
===[[Impetigo]] (2mos and older)=== | |||
*apply ointment TID x 7-14 days | |||
===[[Skin infections]], bacterial (3mos and older)=== | |||
*apply cream TID x 10 days | |||
===Indications by Disease=== | ===Indications by Disease=== | ||
{{#ask: [[Has DrugName::Mupirocin]] [[Has Population::Pediatric]] | {{#ask: [[Has DrugName::Mupirocin]] [[Has Population::Pediatric]] | ||
|?Treats disease=Disease | |?Treats disease=Disease | ||
|?Has Dose=Dose | |?Has Dose=Dose | ||
|?Has Context=Context | |?Has Context=Context | ||
|format=table | |format=table | ||
|limit=50 | |limit=50 | ||
|mainlabel=- | |mainlabel=- | ||
|headers=show | |headers=show | ||
|sort=Treats disease | |sort=Treats disease | ||
}} | }} | ||
Revisión del 02:38 20 mar 2026
General
- Type: Antibiotic, Topical
- Dosage Forms: 2% cream, ointment
- Routes of Administration: topical
- Common Trade Names: Bactroban, Centany
Adult Dosing
Impetigo
- apply ointment TID x 7-14 days
Skin infections, bacterial
- apply cream TID x 10 days
Indications by Disease
| Disease | Dose | Context |
|---|---|---|
| Balanoposthitis | cream BID | Antibacterial |
| Impetigo | 2% ointment q8hrs x 5 days | For nonbullous impetigo, topical antibiotics are as effective as oral antibiotics |
Pediatric Dosing
Impetigo (2mos and older)
- apply ointment TID x 7-14 days
Skin infections, bacterial (3mos and older)
- apply cream TID x 10 days
Indications by Disease
| Disease | Dose | Context |
|---|---|---|
| Impetigo | 2% ointment applied TID x 5 days | Pediatric Topical |
Special Populations
- Pregnancy Rating: B
- Lactation risk: probably safe
Renal Dosing
- Adult: NA
- Pediatric: NA
Hepatic Dosing
- Adult: NA
- Pediatric: NA
Contraindications
- Allergy to class/drug
- large open wounds
- caution if renal impairment, mod-severe
Adverse Reactions
Serious
- hypersensitivity run
- anaphylaxis
- C. difficile-assoc diarrhea
- superinfection (prolonged use)
Common
- nausea
- burning
- headache
- pruritus
- pain
- stinging
Pharmacology
- Half-life: 20-40 min
- Metabolism: liver; CYP450; <0.3% systemic absorption
- Excretion: urine <3%
- Mechanism of Action: bacteriostatic or bactericidal, depending on susceptibility and concentration; reversibly binds to isoleucyl-tRNA synthetase, inhibiting protein synthesis (monoxycarbolic acid)