Diferencia entre revisiones de «Platelet transfusion»

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==General==
==General==
*Type:  
*Type: [[Blood products]]
*Dosage Forms:
*Dosage Forms:
*Common Trade Names:  
*Common Trade Names:


==Adult Dosing==
==Adult Dosing==

Revisión del 17:52 29 may 2015

General

Adult Dosing

Thrombocytopenia

  • 1 unit raises count by 50K

Pediatric Dosing

Special Populations

  • Pregnancy Rating:
  • Lactation:
  • Renal Dosing
    • Adult
    • Pediatric
  • Hepatic Dosing
    • Adult
    • Pediatric

Indications

  • Plt count <10K in asymptomatic patients (unless due to ITP, TTP, or HIT)
  • Plt count <15K with a coagulation disorder or minor bleeding
  • Plt count <20K with major bleeding
  • Plt count <50K with need for invasive procedure or surgery
  • Plt count <100K with need for neurologic or cardiac surgery

Contraindications

  • Allergy to class/drug

Adverse Reactions

Serious

Common

Pharmacology

  • Half-life:
  • Metabolism:
  • Excretion:
  • Mechanism of Action:

Comments

  • Transfusion should be type specific because platelets are bathed in plasma
    • Non-type specific platelets can be used but results in higher rate of complications
  • Like pRBCs, platelets can be leukocyte reduced or washed

See Also

References